GHCM Project
Generalized Heterogeneous Computing Machine

within Topological Neurocybernetics (TND) Program
PRIMUS Center, TETRAD Institute

October 2022:

We are revising the website for this Program and its Projects, in order to add many recent papers and other materials.

A Biologically-Inspired Entanglement-enabled Computer

(Note: "NeoPlexus Project" is now known as the GHCM (Generalized Heterogeneous Computing Machine) Project within the Topological Neurocybernetic Dynamics Program. The term, "Neoplexus" was coined with respectful reference to "Neo" for "new, novel", "Plexus" (pertaining to neural plexuses), and also by indirect reference to "Colossus" and "Bombe" both, of fame as name of the early computing machines that evolved in 1943-1945 within the research by British codebreakers, inluding Tommy Flowers and Alan Turing, especially in the years 1943–1945 as part of the British cryptanalysis efforts to break the Lorenz cipher. (Turing's machine that helped decode Enigma was the electromechanical Bombe machine.)

We do continue to work on GHCM, but beginning in 2021, our concentration now is directed more to the biological foundations which we believe must be the basis for any GHCM architecture in the future. We are in fact concentrating on problems of noise, dissonance, and signal conflict - and how to use models from the biological brain and Central Nervous System to better understand how we must dresign the GHCM of the future. Thus, we direct the reader to the Neuroplex-C Project, which draws upon prior work in this Program and in turn contributes to it as well.

The GHCM is a machine designed to perform tasks which require the parallel, concurrent integration of both classical Turing-type instruction-path logics and quantum computing that includes the qubit-logic approach in many contemporary quantum computer architectures, but also a significantly different model of field-like computing that is modeled upon processes in not only the brain but within other cellular organisms, including viruses and bacteria, a logic that is based upon dynamic and in fact noisy entanglement functions involving large macromolecular arrays.

The concentration of work now is upon advancing our theoretical understanding and models for computation that is performed with arrays of protein-polymer conjugates, in a manner that is consistent with understanding the mechanisms of control exercised at the molecular scale within biological systems, namely eukaryotic cells and also bacteria and viruses.

There are papers and presentations and an extensive bibliography, all of which are available upon request.

Thus, the TND approach to the "quantum computing" dimension of "Generalized Heterogenous Computing" is quite different from the approach that is in the "mainstream" of quantum computing research that is pursuing a different, yes, valuable, and yes, scientifically sound, pathway which is focused upon particular classes of computational problems where massive numerical computations are typically required, and all this in the context of a Turing Machine architecture, not different from the classical, conventional cpomputing machines of the past 75+ years.

We also work in the TND Program on models of how this non-Turing topological-order based form of computation is operating in the higher-order biological network system of the brain and central nervous system. This leads into topological pattern recognition performed by massive networks of neurons in which surfaces of neural regions are perhaps more significant, in understanding how the mammalian brain (for instance) recognizes, learns and remembers phenomena associated with external objects and internal cognitive structures.

We will soon place here a large number of papers written by both Institute scholars and fellows and other colleagues.

Patience, Please, as we have a lot to do!

Please read this preliminary overview document:

Neuroplex-C Project

Also, look at other pages of TETRAD Institute, and PRIMUS Center, where there are papers and presentations at

Take a look at some of the papers connected with control theory and cybernetics, particularly from from 2017-2019!

TETRAD Institute is a private not-for-profit international research organization dedicated to advancement of culture through science, technology, engineering, arts and mathematics, working in collaboration with partners in academia, industry, and others within both the public and private sectors.

Contact: +1 (231) 492-8301 (voice/text/Viber/WhatsApp), +1 (562) 399-2890, +1 (505) 926-1399, martinjoseph (at), rachaelc (at),

Copyright © 2018, 2019, 2020 TETRAD Institute