NeoPlexus Program and GHCM Project
Topological Neurocybernetic Dynamics (TND)
within PRIMUS Center, TETRAD Institute

October 2021:

We are revising the website for this Program and its Projects, in order to add recent papers and other materials.

(Note: "NeoPlexus Program" is now known as the "Topological Neurocybernetic Dynamics Program")

Our concentration now is on the Neuroplex-C Project, which draws upon prior work in this Program and in turn contributes to it as well.

The concentration of work now is upon advancing our theoretical understanding and models for computation that is performed with arrays of protein-polymer conjugates, in a manner that is consistent with understanding the mechanisms of control exercised at the molecular scale within biological systems, namely eukaryotic cells and also bvacteria and viruses.

Thus, the TND approach to the "quantum computing" dimension of "Generalized Heterogenous Computing" is quite different from the approach that is in the "mainstream" of quantum computing research that is pursuing a different, yes, valuable, and yes, scientifically sound, pathway which is focused upon particular classes of computational problems where massive numerical computations are typically required, and all this in the context of a Turing Machine architecture, not different from the classical, conventional cpomputing machines of the past 75+ years.

We also work in the TND Program on models of how this non-turing topological-order based form of computation is operating in the higher-order biological network system of the brain and central nervous system. This leads into topological pattern recognition performed by massive networks of neurons in which surfaces of neural regions are perhaps more significant, in understanding how the mammalian brain (for instance) recognizes, learns and remembers phenomena associated with external objects and internal cognitive structures.

We will soon place here a large number of papers written by both Institute schoalrs and fellows and other colleagues.

Patience, Please, as we have a lot to do!

Please read this preliminary overview document:

Neuroplex-C Project

Also, look at other pages of TETRAD Institute, and PRIMUS Center, where there are papers and presentations at

Take a look at some of the papers connected with control theory and cybernetics!

TETRAD Institute is a private not-for-profit international research organization dedicated to advancement of culture through science, technology, engineering, arts and mathematics, working in collaboration with partners in academia, industry, and others within both the public and private sectors.

Contact: +1 (231) 492-8301 (voice/text/Viber/WhatsApp), +1 (562) 399-2890, +1 (505) 926-1399, martinjoseph (at), rachaelc (at),

Copyright © 2018, 2019, 2020 TETRAD Institute